Mechanism of action of 5-arninosalicylic acid
نویسندگان
چکیده
منابع مشابه
Mechanism of action of 5-arninosalicylic acid
5-Aminosalicylic Acid (5-ASA) has been used for over 50 years in the treatment of inflammatory bowel disease in the pro-drug form sulphasalazine (SASP). SASP is also used to treat rheumatoid arthritis. However whether the therapeutic properties of SASP are due to the intact molecule, the 5-ASA or sulphapyridine components is unknown. Several mechanisms of action have been proposed for 5-ASA and...
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چکیده ندارد.
15 صفحه اولMechanism of action of 5'-nucleotidase.
The enzyme 5’-nucleotidase was originally discovered in the venom of snakes (1) and later shown to be present in mammalian tissues (2-5) and bull seminal plasma (6). It has recently been extensively purified and characterized by Heppel and Hilmoe (7). The enzyme was shown to hydrolyze 5’-nucleotides rapidly, ribose-5-phosphate slowly, and other phosphate esters extremely slowly, if at all. Beca...
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ژورنال
عنوان ژورنال: Mediators of Inflammation
سال: 1992
ISSN: 0962-9351,1466-1861
DOI: 10.1155/s0962935192000243